What is a common side effect of levetiracetam that may affect adherence?

• A. Behavioral changes such as irritability or mood changes
• B. Weight gain
• C. Drowsiness at night
• D. Hair loss

Answer: (A)

Behavioral changes, especially irritability or mood swings, are a common side effect of levetiracetam that can affect adherence. These mood-related symptoms are noticeable and troublesome for many patients, making them more likely to skip doses or stop the medication rather than continue as prescribed. While some people may experience drowsiness, it’s the mood changes that most often interfere with staying on therapy. Weight gain and hair loss are not typical effects of levetiracetam. If mood changes occur, clinicians can consider-dose adjustments, switching therapies if needed, and close monitoring of mood and safety to help patients stay on seizure treatment.